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The Charles River Laboratories BG600 Beta Glucan Blocker is a specialized buffer designed to mitigate interference from (1,3)-β-D glucans in bacterial endotoxin testing using Limulus Amebocyte Lysate assays. This product is crucial for preventing false-positive results caused by the presence of glucans, ensuring reliable detection of endotoxins. It simplifies sample preparation by permitting a 1:1 dilution with the blocker before testing.
Eliminates glucan interference to prevent false-positive reactions in assays.
Enhances assay accuracy for dependable bacterial endotoxin quantification.
Streamlined workflow integrates easily into existing LAL testing protocols.
Supports regulatory compliance by addressing common assay interferences.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Diketone-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
PEG-based PROTAC linker
Can be used in the synthesis of PROTACs
Contains two different ligands connected by a linker
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
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We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. This product has Inherently Safer Chemistry compared to the standard use of phenol and chloroform to perform DNA extractions.
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The GenElute Endotoxin-free Plasmid Kit offers a simple rapid cost effective method for purifying plasmid DNA with 0.1 EU/mug DNA for high efficiency transfection. Endotoxins (also known as lipopolysaccharides or LPS) are often co-purified with plasmid DNA and significantly reduce transfection efficiencies in endotoxin-sensitive cell lines. Recombinant E. coli is harvested from an overnight culture by centrifugation and subjected to a modified alkaline-SDS lysis procedure to produce a cleared lysate. Endotoxins are removed from the cleared lysate with simple extraction-phase separation steps. Plasmid DNA is further purified by adsorption onto silica in the presence of high salts. After a simple spin-wash step the bound plasmid DNA is eluted in endotoxin-free water. Up to 250 mug of endotoxin-free plasmid DNA may be prepared from 5 to 40 mL of culture.The recovered plasmid DNA is predominately in its supercoiled form. The DNA is ready for immediate use in downstream applications su
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